Chromatin remodeling: demethylating H3K4me3 of type I IFNs gene by Rbp2 through interacting with Piasy for transcriptional attenuation

Type I IFNs (IFNIs) are involved in the course of antiviral and antimicrobial activities; however, robust inductions of these can lead to host immunopathology. We have reported that the Pias (protein inhibitor of activated signal transducer and activator of transcription) family member, Piasy, posse...

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Publicat a:FASEB J
Autors principals: Yu, Xiaoli, Chen, Hui, Zuo, Chen, Jin, Xi, Yin, Yibing, Wang, Hong, Jin, Mei, Ozato, Keiko, Xu, Songxiao
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137643/
https://ncbi.nlm.nih.gov/pubmed/28970247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700088RR
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