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An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus
Nodal signaling controls asymmetric organ placement during vertebrate embryogenesis. Nodal is induced by a leftward fluid flow at the ciliated left-right organizer (LRO). The mechanism of flow sensing, however, has remained elusive. pkd2 encodes the calcium channel Polycystin-2, which is required fo...
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| Publicado no: | iScience |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6136938/ https://ncbi.nlm.nih.gov/pubmed/30428378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.03.011 |
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