A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse

Goosecoid (Gsc) expression marks the primary embryonic organizer in vertebrates and beyond. While functions have been assigned during later embryogenesis, the role of Gsc in the organizer has remained enigmatic. Using conditional gain-of-function approaches in Xenopus and mouse to maintain Gsc expre...

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Publicado no:Sci Rep
Principais autores: Ulmer, Bärbel, Tingler, Melanie, Kurz, Sabrina, Maerker, Markus, Andre, Philipp, Mönch, Dina, Campione, Marina, Deißler, Kirsten, Lewandoski, Mark, Thumberger, Thomas, Schweickert, Axel, Fainsod, Abraham, Steinbeißer, Herbert, Blum, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318956/
https://ncbi.nlm.nih.gov/pubmed/28220837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43010
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