The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers

Pathogenic germline variants in ataxia-telangiectasia mutated (ATM), a gene that plays a role in DNA damage response and cell cycle checkpoints, confer an increased breast cancer (BC) risk. Here, we investigated the phenotypic characteristics and landscape of somatic genetic alterations in 24 BCs fr...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Natl Cancer Inst
Κύριοι συγγραφείς: Weigelt, Britta, Bi, Rui, Kumar, Rahul, Blecua, Pedro, Mandelker, Diana L, Geyer, Felipe C, Pareja, Fresia, James, Paul A, Couch, Fergus J, Eccles, Diana M, Blows, Fiona, Pharoah, Paul, Li, Anqi, Selenica, Pier, Lim, Raymond S, Jayakumaran, Gowtham, Waddell, Nic, Shen, Ronglai, Norton, Larry, Wen, Hannah Y, Powell, Simon N, Riaz, Nadeem, Robson, Mark E, Reis-Filho, Jorge S, Chenevix-Trench, Georgia
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2018
Θέματα:
Brief Communications
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136925/
https://ncbi.nlm.nih.gov/pubmed/29506079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy028
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