Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin

BACKGROUND: Most pathogenic mutations in the BRCA2 gene carry a high risk of hereditary breast and ovarian cancer (HBOC). However, a stop-gain mutation, K3326* (rs11571833), confers risk of lung cancer and cancers of the upper-aero-digestive tract but only a modest risk of breast or ovarian cancer....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Rafnar, Thorunn, Sigurjonsdottir, Gudbjorg R, Stacey, Simon N, Halldorsson, Gisli, Sulem, Patrick, Pardo, Luba M, Helgason, Hannes, Sigurdsson, Stefan T, Gudjonsson, Thorkell, Tryggvadottir, Laufey, Olafsdottir, Gudridur H, Jonasson, Jon G, Alexiusdottir, Kristin, Sigurdsson, Asgeir, Gudmundsson, Julius, Saemundsdottir, Jona, Sigurdsson, Jon K, Johannsdottir, Hrefna, Uitterlinden, Andre, Vermeulen, Sita H, Galesloot, Tessel E, Allain, Dawn C, Lacko, Martin, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Johannsson, Oskar T, Sigurdsson, Fridbjorn, Ragnarsson, Gunnar B, Isaksson, Helgi, Hardardottir, Hronn, Gudbjartsson, Tomas, Gudbjartsson, Daniel F, Masson, Gisli, Kiemeney, Lambertus A M L, Ewart Toland, Amanda, Nijsten, Tamar, Peters, Wilbert H M, Olafsson, Jon H, Jonsson, Steinn, Thorsteinsdottir, Unnur, Thorleifsson, Gudmar, Stefansson, Kari
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136924/
https://ncbi.nlm.nih.gov/pubmed/29767749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djy002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados