Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target

Natural Killer (NK) cell-based cancer immunotherapies were often disappointing in the clinic mostly due to insufficient NK cell infiltration into tumors. We found that targeting autophagy induced a massive infiltration of NK cells into melanoma tumors. These findings highlight autophagy inhibition a...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Noman, Muhammad Zaeem, Paggetti, Jerome, Moussay, Etienne, Berchem, Guy, Janji, Bassam
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136884/
https://ncbi.nlm.nih.gov/pubmed/30221048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1452583
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