Microvesicles released from multiple myeloma cells are equipped with ectoenzymes belonging to canonical and non-canonical adenosinergic pathways and produce adenosine from ATP and NAD(+)

Multiple myeloma (MM) derives from malignant transformation of plasma cells (PC), which accumulate in the bone marrow (BM), where microenvironment supports tumor growth and inhibits anti-tumor immune responses. Adenosine (ADO), an immunosuppressive molecule, is produced within MM patients' BM b...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Morandi, F., Marimpietri, D., Horenstein, A. L., Bolzoni, M., Toscani, D., Costa, F., Castella, B., Faini, A. C., Massaia, M., Pistoia, V., Giuliani, N., Malavasi, F.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136872/
https://ncbi.nlm.nih.gov/pubmed/30221054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1458809
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