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A ribonucleoprotein octamer for targeted siRNA delivery
Hurdles in cell-specific delivery of small interfering RNA (siRNA) in vivo hinder the clinical translation of RNA interference (RNAi). A fundamental problem concerns conflicting requirements for the design of the delivery vehicles: cationic materials facilitate cargo condensation and endosomolysis,...
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| Publicado no: | Nat Biomed Eng |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6136846/ https://ncbi.nlm.nih.gov/pubmed/30936447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0214-1 |
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