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Anti-cancer effects of disulfiram in head and neck squamous cell carcinoma via autophagic cell death

BACKGROUND: Disulfiram (DSF), which is used to treat alcohol dependence, has been reported to have anti-cancer effects in various malignant tumors. In this study, we investigated the anti-cancer effects and mechanism of DSF in HNSCC. METHODS: Head and neck squamous carcinoma cell lines (FaDu and Hep...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Park, Young Min, Go, Yoon Young, Shin, Sun Hwa, Cho, Jae-Gu, Woo, Jeong-Soo, Song, Jae-Jun
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136695/
https://ncbi.nlm.nih.gov/pubmed/30212479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203069
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