Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma

Survivin is ubiquitously expressed in patients with head neck squamous cell carcinoma (HNSCC) and is associated with poor survival and chemotherapy resistance. Sepantronium bromide (YM155) is a selective survivin suppressant that exhibits potent antitumor activities by inducing apoptosis and autopha...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, L, Zhang, W, Wang, Y-F, Liu, B, Zhang, W-F, Zhao, Y-F, Kulkarni, A B, Sun, Z-J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669714/
https://ncbi.nlm.nih.gov/pubmed/26018732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.139
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