Platelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells

Delivery of gene therapy as well as of biologic therapeutics is often hampered by the immune response of the subject receiving the therapy. We have reported that effective gene therapy for hemophilia utilizing platelets as a delivery vehicle engenders profound tolerance to the therapeutic product. I...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Immunol
Egile Nagusiak: Luo, Xiaofeng, Chen, Juan, Schroeder, Jocelyn A., Allen, Kenneth P., Baumgartner, Christina K., Malarkannan, Subramaniam, Hu, Jianda, Williams, Calvin B., Shi, Qizhen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136275/
https://ncbi.nlm.nih.gov/pubmed/30237796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01950
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak