Constitutive Vagus Nerve Activation Modulates Immune Suppression in Sepsis Survivors

Patients surviving a septic episode exhibit persistent immune impairment and increased mortality due to enhanced vulnerability to infections. In the present study, using the cecal ligation and puncture (CLP) model of polymicrobial sepsis, we addressed the hypothesis that altered vagus nerve activity...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Rana, Minakshi, Fei-Bloom, Yurong, Son, Myoungsun, La Bella, Andrea, Ochani, Mahendar, Levine, Yaakov A., Chiu, Pui Yan, Wang, Ping, Chavan, Sangeeta S., Volpe, Bruce T., Sherry, Barbara, Diamond, Betty
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135874/
https://ncbi.nlm.nih.gov/pubmed/30237803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02032
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