Blood-Brain Barrier Deterioration and Hippocampal Gene Expression in Polymicrobial Sepsis: An Evaluation of Endothelial MyD88 and the Vagus Nerve

Systemic infection can initiate or exacerbate central nervous system (CNS) pathology, even in the absence of overt invasion of bacteria into the CNS. Recent epidemiological studies have demonstrated that human survivors of sepsis have an increased risk of long-term neurocognitive decline. There is t...

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Udgivet i:PLoS One
Main Authors: Honig, Gerard, Mader, Simone, Chen, Huiyi, Porat, Amit, Ochani, Mahendar, Wang, Ping, Volpe, Bruce T., Diamond, Betty
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720404/
https://ncbi.nlm.nih.gov/pubmed/26790027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144215
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