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Rapid Turnover of the Cardiac L-Type Ca(V)1.2 Channel by Endocytic Recycling Regulates Its Cell Surface Availability
Calcium entry through Ca(V)1.2 L-type calcium channels regulates cardiac contractility. Here, we study the impact of exocytic and post-endocytic trafficking on cell surface channel abundance in cardiomyocytes. Single-molecule localization and confocal microscopy reveal an intracellular Ca(V)1.2 pool...
Kaydedildi:
| Yayımlandı: | iScience |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6135870/ https://ncbi.nlm.nih.gov/pubmed/30267672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.08.012 |
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