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Machine Learning of Toxicological Big Data Enables Read-Across Structure Activity Relationships (RASAR) Outperforming Animal Test Reproducibility

Earlier we created a chemical hazard database via natural language processing of dossiers submitted to the European Chemical Agency with approximately 10 000 chemicals. We identified repeat OECD guideline tests to establish reproducibility of acute oral and dermal toxicity, eye and skin irritation,...

詳細記述

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書誌詳細
出版年:Toxicol Sci
主要な著者: Luechtefeld, Thomas, Marsh, Dan, Rowlands, Craig, Hartung, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135638/
https://ncbi.nlm.nih.gov/pubmed/30007363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy152
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