Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis

Defects in basal autophagy limit the nutrient supply from recycling of intracellular constituents. Despite our understanding of the prosurvival role of macroautophagy/autophagy, how nutrient deprivation, caused by compromised autophagy, affects oncogenic KRAS-driven tumor progression is poorly under...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Lin, H. Helen, Chung, Yiyin, Cheng, Chun-Ting, Ouyang, Ching, Fu, Yong, Kuo, Ching-Ying, Chi, Kevin K., Sadeghi, Maryam, Chu, Peiguo, Kung, Hsing-Jien, Li, Chien-Feng, Limesand, Kirsten H., Ann, David K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Research Paper - Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135591/
https://ncbi.nlm.nih.gov/pubmed/29956571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1450708
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