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MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER
Mitochondrial damage triggers mitochondrial quality control pathways, which act to ensure the health of the mitochondrial network. The turnover of damaged mitochondria by mitophagy is initiated by the Parkinson disease-linked genes PRKN and PINK1, and we recently investigated the role that interorga...
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| Veröffentlicht in: | Autophagy |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6135574/ https://ncbi.nlm.nih.gov/pubmed/30081712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1505154 |
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