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MFN2 retrotranslocation boosts mitophagy by uncoupling mitochondria from the ER

Mitochondrial damage triggers mitochondrial quality control pathways, which act to ensure the health of the mitochondrial network. The turnover of damaged mitochondria by mitophagy is initiated by the Parkinson disease-linked genes PRKN and PINK1, and we recently investigated the role that interorga...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: McLelland, Gian-Luca, Fon, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135574/
https://ncbi.nlm.nih.gov/pubmed/30081712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1505154
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