Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy

Integrating functional and molecular levels, we investigated the effects of maternal treatment with a xanthine oxidase inhibitor on the programming of cardiac dysfunction in adult offspring using an established rat model of hypoxic pregnancy. Female Wistar rats were divided into normoxic or hypoxic...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Niu, Youguo, Kane, Andrew D., Lusby, Ciara M., Allison, Beth J., Chua, Yi Yi, Kaandorp, Joepe J., Nevin-Dolan, Rhiannon, Ashmore, Thomas J., Blackmore, Heather L., Derks, Jan B., Ozanne, Susan E., Giussani, Dino A.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott, Williams & Wilkins 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135482/
https://ncbi.nlm.nih.gov/pubmed/30354714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11363
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