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Anti-HER2 functionalized graphene oxide as survivin-siRNA delivery carrier inhibits breast carcinoma growth in vitro and in vivo

BACKGROUND: The success of gene therapy is mostly dependent on the development of gene carrier. Graphene oxide (GO) possesses excellent aqueous solubility and biocompatibility, which is important for its biochemical and medical applications. Our previous work proved that GO can deliver siRNA into ce...

Полное описание

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Библиографические подробности
Опубликовано в: :Drug Des Devel Ther
Главные авторы: Wang, Xiaoli, Sun, Qi, Cui, Chunying, Li, Jing, Wang, Yifan
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135080/
https://ncbi.nlm.nih.gov/pubmed/30233146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S169430
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