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Quantitative Adverse Outcome Pathways and Their Application to Predictive Toxicology

A quantitative adverse outcome pathway (qAOP) consists of one or more biologically based, computational models describing key event relationships linking a molecular initiating event (MIE) to an adverse outcome. A qAOP provides quantitative, dose-response and time-course predictions that can support...

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Bibliografiske detaljer
Udgivet i:Environ Sci Technol
Main Authors: Conolly, Rory B., Ankley, Gerald T., Cheng, WanYun, Mayo, Michael L., Miller, David H., Perkins, Edward J., Villeneuve, Daniel L., Watanabe, Karen H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134852/
https://ncbi.nlm.nih.gov/pubmed/28355063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.6b06230
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