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Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

Last decade witnessed an enormous progress in generating authentic infectious prions or PrP(Sc) in vitro using recombinant prion protein (rPrP). Previous work established that rPrP that lacks posttranslational modification is able to support replication of highly infectious PrP(Sc) with assistance o...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Makarava, Natallia, Savtchenko, Regina, Lasch, Peter, Beekes, Michael, Baskakov, Ilia V.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134792/
https://ncbi.nlm.nih.gov/pubmed/30208966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0597-y
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