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Mucosal associated invariant T cells from human breast ducts mediate a Th17-skewed response to bacterially exposed breast carcinoma cells

BACKGROUND: Antimicrobial T cells play key roles in the disease progression of cancers arising in mucosal epithelial tissues, such as the colon. However, little is known about microbe-reactive T cells within human breast ducts and whether these impact breast carcinogenesis. METHODS: Epithelial ducts...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Zumwalde, Nicholas A., Haag, Jill D., Gould, Michael N., Gumperz, Jenny E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134631/
https://ncbi.nlm.nih.gov/pubmed/30208917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-018-1036-5
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