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Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosynthetic pathway

Antimicrobial and anti-proliferative meleagrin and oxaline are roquefortine C-derived alkaloids produced by fungi of the genus Penicillium. Tandem O-methylations complete the biosynthesis of oxaline from glandicoline B through meleagrin. Currently, little is known about the role of these methylation...

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Bibliografische gegevens
Gepubliceerd in:Org Biomol Chem
Hoofdauteurs: Newmister, Sean A., Romminger, Stelamar, Schmidt, Jennifer J., Williams, Robert M., Smith, Janet L., Berlinck, Roberto G. S., Sherman, David H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134404/
https://ncbi.nlm.nih.gov/pubmed/30141817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob01565a
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