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β-Adrenergic receptors control brown adipose UCP-1 tone and cold response without affecting its circadian rhythmicity
Brown adipose tissue (BAT) thermogenic functions are primarily mediated by uncoupling protein (UCP)-1. Ucp1 gene expression is highly induced by cold temperature, via sympathetic nervous system and β-adrenergic receptors (βARs). Ucp1 is also repressed by the clock gene Rev-erbα, contributing to its...
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| Wydane w: | FASEB J |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Federation of American Societies for Experimental Biology
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6133705/ https://ncbi.nlm.nih.gov/pubmed/29715048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800452R |
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