Peripheral Circadian Clock Rhythmicity Is Retained in the Absence of Adrenergic Signaling

OBJECTIVE: The incidence of heart attack and stroke undergo diurnal variation. Molecular clocks have been described in the heart and the vasculature; however it is largely unknown how the suprachiasmatic nucleus (SCN) entrains these peripheral oscillators. METHODS AND RESULTS: Norepinephrine and epi...

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Main Authors: Reilly, Dermot F., Curtis, Anne M., Cheng, Yan, Westgate, Elizabeth J., Rudic, Radu D., Paschos, Georgios, Morris, Jacqueline, Ouyang, Ming, Thomas, Steven A., FitzGerald, Garret A.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752700/
https://ncbi.nlm.nih.gov/pubmed/17975121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.107.152538
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