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Lysosomal membrane permeabilization causes secretion of IL-1β in human vascular smooth muscle cells
OBJECTIVE: IL-1β secretion by the inflammasome is strictly controlled and requires two sequential signals: a priming signal and an activating signal. Lysosomal membrane permeabilization (LMP) plays a critical role in the regulation of NLRP3 inflammasome, and generally acts as an activating signal. H...
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| Publicado no: | Inflamm Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6133165/ https://ncbi.nlm.nih.gov/pubmed/30136196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-018-1178-z |
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