MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways

MicroRNAs (miRNA) regulate fundamental biological processes, including neuronal plasticity, stress response, and survival. Here, we describe a neuroprotective function of miR-132, the miRNA most significantly downregulated in neurons in Alzheimer’s disease. We demonstrate that miR-132 protects prima...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: El Fatimy, Rachid, Li, Shaomin, Chen, Zhicheng, Mushannen, Tasnim, Gongala, Sree, Wei, Zhiyun, Balu, Darrick T., Rabinovsky, Rosalia, Cantlon, Adam, Elkhal, Abdallah, Selkoe, Dennis J., Sonntag, Kai C., Walsh, Dominic M., Krichevsky, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132948/
https://ncbi.nlm.nih.gov/pubmed/29982852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1880-5
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