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Backbone (1)H, (13)C, and (15)N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

The glucocorticoid receptor (GR) is a nuclear hormone receptor that regulates key genes controlling development, metabolism, and the immune response. GR agonists are efficacious for treatment of inflammatory, allergic, and immunological disorders. Steroid hormone binding to the ligand-binding domain...

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Bibliografische gegevens
Gepubliceerd in:Biomol NMR Assign
Hoofdauteurs: Köhler, Christian, Carlström, Göran, Tångefjord, Stefan, Papavoine, Tineke, Lepistö, Matti, Edman, Karl, Akke, Mikael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Netherlands 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132842/
https://ncbi.nlm.nih.gov/pubmed/29667121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-018-9820-9
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