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Increased serum levels of sortilin-derived propeptide after electroconvulsive therapy in treatment-resistant depressed patients

PURPOSE: Sortilin-derived propeptide (PE) and its synthetic analog spadin show strong antidepressant activity in rodents and, therefore, could be used as a biomarker to evaluate the clinical efficacy of antidepressant treatments. The aim of this study was to determine whether electroconvulsive thera...

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Detalhes bibliográficos
Publicado no:Neuropsychiatr Dis Treat
Main Authors: Roulot, Morgane, Minelli, Alessandra, Bortolomasi, Marco, Maffioletti, Elisabetta, Gennarelli, Massimo, Borsotto, Marc, Heurteaux, Catherine, Mazella, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132490/
https://ncbi.nlm.nih.gov/pubmed/30233189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S170165
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