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Effect of Dose and 5α‐Reductase Inhibition on the Circulating Testosterone Metabolite Profile of Men Administered Oral Testosterone

Development of an oral testosterone therapy has proven extremely challenging because of extensive and variable first‐pass metabolism. We investigated the in vivo metabolism of testosterone with increasing oral doses of testosterone, both alone and with the co‐administration of dutasteride (5α‐reduct...

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Bibliografske podrobnosti
izdano v:Clin Transl Sci
Main Authors: Basit, Abdul, Amory, John K., Prasad, Bhagwat
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132360/
https://ncbi.nlm.nih.gov/pubmed/29877607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12569
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