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Effect of Dose and 5α‐Reductase Inhibition on the Circulating Testosterone Metabolite Profile of Men Administered Oral Testosterone

Development of an oral testosterone therapy has proven extremely challenging because of extensive and variable first‐pass metabolism. We investigated the in vivo metabolism of testosterone with increasing oral doses of testosterone, both alone and with the co‐administration of dutasteride (5α‐reduct...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Basit, Abdul, Amory, John K., Prasad, Bhagwat
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132360/
https://ncbi.nlm.nih.gov/pubmed/29877607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12569
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