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Identification of a BRCA2 mutation in a Turkish family with early‐onset breast cancer

We used a multi‐gene panel testing to identify the germline variants in a mother‐daughter pair with early‐onset breast cancer, and detected one pathogenic protein‐truncating variant in BRCA2. Our results highlight the importance of genetic testing in identifying the pathogenic mutation running in ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Case Rep
Hauptverfasser: Celik, Elifnaz, Ermis Tekkus, Kubra, Akcay, Izzet Mehmet, Alkurt Sal, Gizem, Ezberci, Fikret, Dinler Doganay, Gizem, Doganay, Levent
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132100/
https://ncbi.nlm.nih.gov/pubmed/30214756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.1625
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