Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single Cell Sequencing

Triple-negative breast cancer (TNBC) is an aggressive subtype that frequently develops resistance to chemotherapy. An unresolved question is whether resistance is caused by the selection of rare pre-existing clones or alternatively through the acquisition of new genomic aberrations. To investigate t...

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Udgivet i:Cell
Main Authors: Kim, Charissa, Gao, Ruli, Sei, Emi, Brandt, Rachel, Hartman, Johan, Hatschek, Thomas, Crosetto, Nicola, Foukakis, Theodoros, Navin, Nicholas
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132060/
https://ncbi.nlm.nih.gov/pubmed/29681456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.041
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