Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson’s Disease

Animal models have significantly advanced our understanding of Parkinson’s disease (PD). Alpha-synuclein (α-syn) has taken center stage due to its genetic connection to familial PD and localization to Lewy bodies, one pathological hallmark of PD. Animal models developed on the premise of elevated al...

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Bibliografiset tiedot
Julkaisussa:Front Neurosci
Päätekijät: Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Fischer, D. Luke, Stoll, Anna C., Sortwell, Caryl E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Neuroscience
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132025/
https://ncbi.nlm.nih.gov/pubmed/30233303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00621
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