Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol

BACKGROUND: Inflammation has been proposed to contribute to the decline in adult hippocampal neurogenesis. Proinflammatory cytokines activate transcription of chemokine growth-regulated oncogene α (Gro1) in human and murine hippocampal neuronal progenitor cells (NPC). The goal of this study was to i...

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Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Zonis, Svetlana, Breunig, Joshua J., Mamelak, Adam, Wawrowsky, Kolja, Bresee, Catherine, Ginzburg, Nadiya, Chesnokova, Vera
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131894/
https://ncbi.nlm.nih.gov/pubmed/30201019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1298-y
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