The Fluorescent D-Amino Acid NADA as a Tool to Study the Conditional Activity of Transpeptidases in Escherichia coli

The enzymes responsible for the synthesis of the peptidoglycan (PG) layer constitute a fundamental target for a large group of antibiotics. The family of β-lactam antibiotics inhibits the DD-transpeptidase (TPase) activity of the penicillin binding proteins (PBPs), whereas its subgroup of carbapenem...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Montón Silva, Alejandro, Otten, Christian, Biboy, Jacob, Breukink, Eefjan, VanNieuwenhze, Michael, Vollmer, Waldemar, den Blaauwen, Tanneke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131605/
https://ncbi.nlm.nih.gov/pubmed/30233559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02101
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