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Alanine Scanning Mutagenesis of the C-Terminal Cytosolic End of Gpm6a Identifies Key Residues Essential for the Formation of Filopodia

Neuronal membrane glycoprotein M6a (Gpm6a) is a protein with four transmembrane regions and the N- and the C-ends facing the cytosol. It functions in processes of neuronal development, outgrowth of neurites, and formation of filopodia, spines, and synapsis. Molecular mechanisms by which Gpm6a acts i...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Rosas, Nicolás M., Alvarez Juliá, Anabel, Alzuri, Sofia E., Frasch, Alberto C., Fuchsova, Beata
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131581/
https://ncbi.nlm.nih.gov/pubmed/30233315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00314
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