Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana

Agroinfiltrated Nicotiana benthamiana is a flexible and scalable platform for recombinant protein (RP) production, but its great potential is hampered by plant proteases that degrade RPs. Here, we tested 29 candidate protease inhibitors (PIs) in agroinfiltrated N. benthamiana leaves for enhancing ac...

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Publicat a:Plant Biotechnol J
Autors principals: Grosse‐Holz, Friederike, Madeira, Luisa, Zahid, Muhammad Awais, Songer, Molly, Kourelis, Jiorgos, Fesenko, Mary, Ninck, Sabrina, Kaschani, Farnusch, Kaiser, Markus, van der Hoorn, Renier A.L.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131417/
https://ncbi.nlm.nih.gov/pubmed/29509983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12916
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