Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana

Agroinfiltrated Nicotiana benthamiana is a flexible and scalable platform for recombinant protein (RP) production, but its great potential is hampered by plant proteases that degrade RPs. Here, we tested 29 candidate protease inhibitors (PIs) in agroinfiltrated N. benthamiana leaves for enhancing ac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Plant Biotechnol J
Prif Awduron: Grosse‐Holz, Friederike, Madeira, Luisa, Zahid, Muhammad Awais, Songer, Molly, Kourelis, Jiorgos, Fesenko, Mary, Ninck, Sabrina, Kaschani, Farnusch, Kaiser, Markus, van der Hoorn, Renier A.L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131417/
https://ncbi.nlm.nih.gov/pubmed/29509983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12916
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