Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana

Agroinfiltrated Nicotiana benthamiana is a flexible and scalable platform for recombinant protein (RP) production, but its great potential is hampered by plant proteases that degrade RPs. Here, we tested 29 candidate protease inhibitors (PIs) in agroinfiltrated N. benthamiana leaves for enhancing ac...

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Detalhes bibliográficos
Publicado no:Plant Biotechnol J
Main Authors: Grosse‐Holz, Friederike, Madeira, Luisa, Zahid, Muhammad Awais, Songer, Molly, Kourelis, Jiorgos, Fesenko, Mary, Ninck, Sabrina, Kaschani, Farnusch, Kaiser, Markus, van der Hoorn, Renier A.L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131417/
https://ncbi.nlm.nih.gov/pubmed/29509983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12916
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