Characterization of the hypersensitive response‐like cell death phenomenon induced by targeting antiviral lectin griffithsin to the secretory pathway

Griffithsin (GRFT) is an antiviral lectin, originally derived from a red alga, which is currently being investigated as a topical microbicide to prevent transmission of human immunodeficiency virus (HIV). Targeting GRFT to the apoplast for production in Nicotiana benthamiana resulted in necrotic sym...

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Bibliografiske detaljer
Udgivet i:Plant Biotechnol J
Main Authors: Kim, Bo Min, Lotter‐Stark, Hester Catharina Therese, Rybicki, Edward P., Chikwamba, Rachel K., Palmer, Kenneth E.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131415/
https://ncbi.nlm.nih.gov/pubmed/29509998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12917
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