Platelet activation and prothrombotic properties in a mouse model of peritoneal sepsis

Sepsis is associated with thrombocytopenia and microvascular thrombosis. Studies have described platelets implication in this pathology but their kinetics of activation and behavior remain poorly known. We show in a mouse model of peritonitis, the appearance of platelet-rich thrombi in organ microve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vardon Bounes, Fanny, Mémier, Vincent, Marcaud, Marina, Jacquemin, Aemilia, Hamzeh-Cognasse, Hind, Garcia, Cédric, Series, Jennifer, Sié, Pierre, Minville, Vincent, Gratacap, Marie-Pierre, Payrastre, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131186/
https://ncbi.nlm.nih.gov/pubmed/30201980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31910-8
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