Platelet activation and prothrombotic properties in a mouse model of peritoneal sepsis

Sepsis is associated with thrombocytopenia and microvascular thrombosis. Studies have described platelets implication in this pathology but their kinetics of activation and behavior remain poorly known. We show in a mouse model of peritonitis, the appearance of platelet-rich thrombi in organ microve...

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Publicat a:Sci Rep
Autors principals: Vardon Bounes, Fanny, Mémier, Vincent, Marcaud, Marina, Jacquemin, Aemilia, Hamzeh-Cognasse, Hind, Garcia, Cédric, Series, Jennifer, Sié, Pierre, Minville, Vincent, Gratacap, Marie-Pierre, Payrastre, Bernard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131186/
https://ncbi.nlm.nih.gov/pubmed/30201980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31910-8
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