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Long-term Contractile Activity and Thyroid Hormone Supplementation Produce Engineered Rat Myocardium with Adult-like Structure and Function

The field of cardiac tissue engineering has developed rapidly, but structural and functional immaturity of engineered heart tissues hinder their widespread use. Here, we show that a combination of lowrate (0.2 Hz) contractile activity and thyroid hormone (T3) supplementation significantly promote st...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Jackman, Christopher, Li, Hanjun, Bursac, Nenad
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6131056/
https://ncbi.nlm.nih.gov/pubmed/30086384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.08.003
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