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Dynamic culture yields engineered myocardium with near-adult functional output

Engineered cardiac tissues hold promise for cell therapy and drug development, but exhibit inadequate function and maturity. In this study, we sought to significantly improve the function and maturation of rat and human engineered cardiac tissues. We developed dynamic, free-floating culture conditio...

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Bibliographic Details
Published in:Biomaterials
Main Authors: Jackman, Christopher P., Carlson, Aaron L., Bursac, Nenad
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074846/
https://ncbi.nlm.nih.gov/pubmed/27723557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.09.024
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