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Multiple regions in the extracellular domain of the glycine receptor determine receptor activity

Glycine receptors (GlyRs) are Cys-loop receptors that mediate fast synaptic inhibition in the brain stem and spinal cord. They are involved in the generation of motor rhythm, reflex circuit coordination, and sensory signal processing and therefore represent targets for therapeutic interventions. The...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Tang, Bijun, Lummis, Sarah C. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130964/
https://ncbi.nlm.nih.gov/pubmed/29941455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003088
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