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Walking a fine line between β-cell secretion and proliferation

Of the many common genetic variants associated with type 2 diabetes, that in TCF7L2 remains the most studied because it has the greatest effect size. However, the mechanism by which this variant alters diabetes risk remains elusive. A new study adds another layer of complexity, suggesting that the e...

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Pubblicato in:J Biol Chem
Autori principali: Vella, Adrian, Matveyenko, Aleksey
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130962/
https://ncbi.nlm.nih.gov/pubmed/30194258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H118.005121
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