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Endogenous Retroviruses Walk a Fine Line between Priming and Silencing

Endogenous retroviruses (ERVs) in mammals are closely related to infectious retroviruses and utilize host tRNAs as a primer for reverse transcription and replication, a hallmark of long terminal repeat (LTR) retroelements. Their dependency on tRNA makes these elements vulnerable to targeting by smal...

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Bibliografske podrobnosti
izdano v:Viruses
Main Authors: Cullen, Harrison, Schorn, Andrea J.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472051/
https://ncbi.nlm.nih.gov/pubmed/32718022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12080792
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