Interaction of the α7-nicotinic subunit with its human-specific duplicated dupα7 isoform in mammalian cells: Relevance in human inflammatory responses

The α7 nicotinic receptor subunit and its partially duplicated human-specific dupα7 isoform are coexpressed in neuronal and non-neuronal cells. In these cells, α7 subunits form homopentameric α7 nicotinic acetylcholine receptors (α7-nAChRs) implicated in numerous pathologies. In immune cells, α7-nAC...

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Foilsithe in:J Biol Chem
Main Authors: Maldifassi, María C., Martín-Sánchez, Carolina, Atienza, Gema, Cedillo, José L., Arnalich, Francisco, Bordas, Anna, Zafra, Francisco, Giménez, Cecilio, Extremera, María, Renart, Jaime, Montiel, Carmen
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130954/
https://ncbi.nlm.nih.gov/pubmed/30006348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003443
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