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Effects of Ginkgo leaf tablets on the pharmacokinetics of losartan and its metabolite EXP3174 in rats and its mechanism

Context: Ginkgo leaf tablets (GLTs) and losartan are often simultaneously used for the treatment of hypertension in Chinese clinics. However, the herb–drug interaction between GLT and losartan is still unknown. Objective: This study investigates the effects of GLT on the pharmacokinetics of losartan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharm Biol
Hauptverfasser: Dong, Baiping, Yuan, Suowei, Hu, Jinsheng, Yan, Yanzhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130633/
https://ncbi.nlm.nih.gov/pubmed/29953302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2018.1481107
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