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Effects of ticlopidine on pharmacokinetics of losartan and its main metabolite EXP-3174 in rats
AIM: Losartan and antiplatelet agent ticlopidine can be prescribed concomitantly for prevention or therapy of cardiovascular diseases. Hence, the effects of ticlopidine on the pharmacokinetics of losartan and its active metabolite EXP-3174 were evaluated in rats. METHODS: Ticlopidine (4 or 10 mg/kg...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003123/ https://ncbi.nlm.nih.gov/pubmed/21666702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.32 |
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